Thomas J Briner

Title: Thomas J Briner: Innovator in Therapeutic Proteins and Drug Abuse Therapy

Introduction

Thomas J Briner is a notable inventor based in Arlington, MA (US). He has made significant contributions to the field of therapeutic proteins and drug abuse therapy. With a total of 4 patents, his work has had a meaningful impact on medical research and treatment methodologies.

Latest Patents

One of Briner's latest patents is focused on a human T cell reactive feline protein (TRFP) isolated from house dust. This invention involves a substantially pure, covalently linked TRFP that has been isolated from vacuum bag extract obtained by affinity purification of house dust collected from homes with cats. The patent also covers DNA encoding all or a portion of the TRFP or peptide, as well as compositions containing such proteins or peptides. Additionally, it includes antibodies that are reactive with the TRFP or peptide. The patent further discusses recombinant TRFP or peptide, modified or mutated TRFP peptides, and their applications for diagnostic or therapeutic purposes.

Another significant patent by Briner involves hapten-carrier conjugates for use in drug-abuse therapy. This invention describes hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo. The methods of preparing these conjugates and therapeutic compositions are also disclosed. Particularly, when the hapten is a drug of abuse, the therapeutic composition containing the hapten-carrier conjugate is useful in treating drug addiction, especially cocaine addiction. Passive immunization using antibodies raised against these conjugates is also part of this patent.

Career Highlights

Throughout his career, Thomas J Briner has worked with various companies, including Immulogic Pharmaceutical Corporation and Immulogic, Inc. His work in these organizations has contributed to advancements in therapeutic solutions and drug addiction treatments.

Collaborations

Briner has collaborated with notable individuals in his field, including Julia L Greenstein and Malcolm L Gefter. These collaborations have likely enriched his research and development efforts.

Conclusion

Thomas J Briner is a distinguished inventor whose work in therapeutic proteins and drug abuse therapy has led to valuable patents and advancements in medical science. His contributions continue to influence the field and offer hope for improved treatment options.