The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2000

Filed:

Jun. 27, 1997
Applicant:
Inventors:

Philip A Swain, Boston, MA (US);

Victoria C Schad, Cambridge, MA (US);

Julia L Greenstein, West Newton, MA (US);

Mark A Exley, Chestnut Hill, MA (US);

Barbara S Fox, Wayland, MA (US);

Stephen P Powers, Waltham, MA (US);

Malcolm L Gefter, Lincoln, MA (US);

Thomas J Briner, Arlington, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
4241941 ; 4242361 ; 4242041 ; 4242611 ; 530403 ; 530405 ; 546124 ; 546129 ; 546130 ; 546132 ;
Abstract

Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo are disclosed. Methods of preparing the hapten-carrier conjugates and therapeutic compositions are also disclosed. Where the hapten is a drug of abuse, a therapeutic composition containing the hapten-carrier conjugate is particularly useful in the treatment of drug addiction, more particularly, cocaine addiction. Passive immunization using antibodies raised against conjugates of the instant invention is also disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs.


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