Company Filing History:
Years Active: 1990-1993
Title: Thomas G Warren: Innovator in Modified Tissue Plasminogen Activators
Introduction
Thomas G Warren is a notable inventor based in Ballwin, MO (US). He has made significant contributions to the field of biochemistry, particularly in the development of modified tissue plasminogen activators. With a total of 4 patents to his name, Warren's work has the potential to impact medical treatments significantly.
Latest Patents
Warren's latest patents include innovative modifications to tissue plasminogen activators. One of his patents is for a modified tissue plasminogen activator with a modified glycosylation site. This invention features a t-PA that has an improved in vivo half-life, comprising a fibronectin finger-like domain F, a growth factor domain GF, a sequence of two K2 kringle regions, and a serine protease region SP. Notably, the first kringle is free of any glycosylation site, while the second kringle contains a single glycosylation site. Another significant patent is for a modified tissue plasminogen activator K2K2SP, which also boasts an improved in vivo half-life and includes a sequence of two K2 kringle regions along with a serine protease region SP.
Career Highlights
Warren has built a distinguished career at Monsanto Company, where he has been able to apply his expertise in biochemistry to develop groundbreaking medical solutions. His work has not only advanced the field but has also contributed to the company's reputation as a leader in agricultural and biotechnology innovations.
Collaborations
Throughout his career, Warren has collaborated with esteemed colleagues, including Leslie D Bell and Ernest J Mayer. These partnerships have fostered a collaborative environment that encourages innovation and the sharing of ideas.
Conclusion
Thomas G Warren's contributions to the field of modified tissue plasminogen activators exemplify the impact of innovative thinking in biochemistry. His patents reflect a commitment to improving medical treatments and advancing scientific knowledge.