The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 31, 1992

Filed:

Jun. 06, 1988
Applicant:
Inventors:

Leslie D Bell, Chesterfield, MO (US);

Ernest J Mayer, St. Louis, MO (US);

Mark O Palmier, Webster Groves, MO (US);

H Eser Tolunay, Creve Coeur, MO (US);

Thomas G Warren, Ballwin, MO (US);

Tze-Chein Wun, St. Louis, MO (US);

Assignee:

Monsanto Company, St. Louis, MO (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12P / ; A61K / ;
U.S. Cl.
CPC ...
424 9464 ; 435212 ; 435219 ; 435226 ; 4352402 ; 4353201 ; 536 27 ; 424 9463 ;
Abstract

A modified t-PA having improved in vivo half-life is disclosed comprising in sequence a sequence of two K2 kringle regions and a serine protease region SP.


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