Company Filing History:
Years Active: 1995-1999
Title: Thomas G Laffler: Innovator in Nucleic Acid Detection and Amplification
Introduction
Thomas G Laffler is a notable inventor based in Libertyville, IL (US). He has made significant contributions to the field of molecular biology, particularly in the detection and amplification of nucleic acids. With a total of 4 patents to his name, Laffler's work has advanced the methodologies used in genetic research and diagnostics.
Latest Patents
Laffler's latest patents include innovative methods for the detection and amplification of target nucleic acid sequences. One of his patents discloses a method and kits for amplifying and detecting target nucleic acid sequences in a sample. This method employs primers that have reactive pair members linked to them, which can be attached to a solid phase and/or detected by labeled conjugate. Another significant patent involves methods of improving ligation chain reaction (LCR) and polymerase chain reaction (PCR) amplification schemes. This invention modifies at least one probe/primer end to reduce the probability of spurious signal development. Only after specific hybridization of the modified probe/primer with the true target are the modified ends 'corrected' in a target-dependent fashion, allowing participation in the enzymatic assembly reaction.
Career Highlights
Throughout his career, Thomas G Laffler has worked with prominent companies in the biotechnology sector, including Abbott Laboratories Corporation and Abbott Molecular Inc. His experience in these organizations has contributed to his expertise in developing innovative solutions for nucleic acid detection.
Collaborations
Laffler has collaborated with notable professionals in his field, including John J Carrino and Ronald L Marshall. These collaborations have likely enriched his research and development efforts, leading to impactful innovations.
Conclusion
Thomas G Laffler's contributions to the field of nucleic acid detection and amplification have established him as a significant inventor. His patents reflect a commitment to advancing scientific methodologies, and his collaborations further enhance the impact of his work.
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