Location History:
- Wayland, MA (US) (2009)
- Acton, MA (US) (2002 - 2013)
Company Filing History:
2 out of 389 
2 out of 1,309 
1 out of 6 Years Active: 2002-2013
Title: Thomas E. McDonagh: Innovator in Therapeutic Compounds
Introduction: Thomas E. McDonagh, a distinguished inventor based in Wayland, MA, has made significant contributions in the field of biochemistry through his innovative patents. With a portfolio encompassing five patents, McDonagh's work primarily focuses on developing therapeutic compounds aimed at treating various disorders.
Latest Patents: Among his latest inventions are two notable patents related to SirT inhibitors and aggrecanase structure. The first patent deals with SirT inhibitors that bind to NAD, detailing a compound of formula (I) and methods for treating numerous disorders, including neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders. The second patent focuses on aggrecanase polypeptides, involving aggrecanase polypeptide/ligand complexes, crystals of these complexes, and associated methods and software systems.
Career Highlights: Thomas E. McDonagh has an extensive background in the biopharmaceutical industry, having worked for prestigious organizations such as Genetics Institute, Inc. and Wyeth. His experience in these companies has provided him with a strong foundation in research and development, influencing his innovative endeavors.
Collaborations: Throughout his career, McDonagh collaborated with notable professionals, including Guang-Yi Xu and Christopher John Corcoran. These partnerships have further enriched his research, leading to groundbreaking advancements in therapeutic innovations.
Conclusion: Thomas E. McDonagh exemplifies the spirit of innovation in the biopharmaceutical sector. With a strong patent portfolio and a history of collaborative efforts, his contributions continue to pave the way for new therapeutic solutions to combat various health challenges. His work not only reflects his dedication to scientific progress but also highlights the importance of inventors in improving global health outcomes.