Thomas D Hurley

Title: Thomas D Hurley: Innovator in Cancer Treatment

Introduction

Thomas D Hurley is a prominent inventor based in Indianapolis, ID (US). He has made significant contributions to the field of cancer treatment through his innovative research and patented technologies. With a total of 2 patents, Hurley has focused on developing methods that enhance the efficacy of cancer therapies.

Latest Patents

Hurley's latest patents include "Regulators of aldehyde dehydrogenase ALDH3A1 and related therapeutic methods." This patent describes compositions and methods for treating cancers characterized by high levels of ALDH3A1 activity, which is associated with chemoresistance to certain chemotherapeutic agents. The compositions act as competitive inhibitors of ALDH3A1, thereby reducing the breakdown of chemotherapeutics and increasing their effectiveness in cancer treatment. Another notable patent is "Crystal structure of aldehyde dehydrogenase and methods of use thereof." This patent provides a crystal structure of aldehyde dehydrogenase (ALDH) with a modulator bound to it, along with a method for computationally identifying compounds that bind to ALDH polypeptides.

Career Highlights

Throughout his career, Thomas D Hurley has worked with esteemed institutions such as Indiana University and Stanford University. His research has significantly advanced the understanding of cancer treatment and the role of aldehyde dehydrogenase in chemoresistance.

Collaborations

Hurley has collaborated with notable colleagues, including Che-Hong Chen and Daria D Mochly-Rosen. These partnerships have further enriched his research and contributed to the development of innovative therapeutic methods.

Conclusion

Thomas D Hurley is a key figure in the field of cancer research, with a focus on enhancing treatment efficacy through innovative methods. His contributions continue to impact the landscape of cancer therapy and offer hope for improved patient outcomes.