The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 28, 2012
Filed:
May. 04, 2009
Che-hong Chen, Fremont, CA (US);
Daria Mochly-rosen, Menlo Park, CA (US);
Thomas D. Hurley, Indianapolis, ID (US);
Che-Hong Chen, Fremont, CA (US);
Daria Mochly-Rosen, Menlo Park, CA (US);
Thomas D. Hurley, Indianapolis, ID (US);
The Board of Trustees of the Leland Stanford Junior University, Palo Alto, CA (US);
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Abstract
The present disclosure provides a crystal structure of aldehyde dehydrogenase (ALDH) with a modulator of ALDH bound thereto. The present disclosure provides a computer readable medium comprising atomic coordinates for an ALDH polypeptide and a modulator bound to a site within the polypeptide. A method is also provided. In general terms, the method comprises computationally identifying a compound that binds to an ALDH polypeptide, using the atomic coordinates.