Thomas Cushman Ransohoff

Title: The Innovative Contributions of Thomas Cushman Ransohoff

Introduction

Thomas Cushman Ransohoff is a notable inventor residing in Lexington, MA, USA. He holds five patents to his name, reflecting his significant contributions to the field of biotechnology, particularly in the purification of tissue plasminogen activator (tPA).

Latest Patents

Ransohoff's latest patents focus on innovative methods for obtaining affinity ligands designed to isolate tissue-type plasminogen activator (tPA). He disclosed techniques for developing ligands that bind to tPA with high specificity at a neutral pH of 7 and release it at an acidic pH of 5 or lower. Additionally, Ransohoff's patents detail processes for isolating further ligands that possess desirable preselected binding and release characteristics, allowing for tailored solutions to address specific purification challenges presented by various feed streams containing tPA.

Career Highlights

Throughout his career, Ransohoff has made substantial strides in his field by applying his expertise in biochemistry and molecular biology. His work has been instrumental in enhancing the methods associated with the purification of proteins, notably in therapeutic applications that are crucial in medical treatments.

Collaborations

In his professional journey, Ransohoff has collaborated with notable individuals, such as John Moore Maclennan and Robert Charles Ladner. These collaborations have furthered his research and development efforts, leading to the innovative breakthroughs that characterize his patents.

Conclusion

Thomas Cushman Ransohoff’s contributions to the field of biotechnology through his patents and collaborations signify his role as a pivotal inventor in advancing methods for the purification of tPA. His work continues to impact the medical industry positively, demonstrating the importance of innovation in solving complex scientific challenges.