Tehila Ben-Moshe

Title: Tehila Ben-Moshe: Innovator in Protein Therapeutics

Introduction

Tehila Ben-Moshe is a prominent inventor based in Koranit, Israel. She has made significant contributions to the field of protein therapeutics, holding a total of 9 patents. Her work focuses on innovative solutions for medical conditions, particularly in the realm of enzyme therapies and antibody development.

Latest Patents

Among her latest patents is the invention of stabilized alpha-galactosidase and its applications. This patent describes multimeric protein structures that consist of at least two alpha-galactosidase monomers covalently linked through a linking moiety. The process for preparing these structures and their use in treating Fabry disease is also detailed. These multimeric protein structures demonstrate improved performance, showcasing enhanced activity and prolonged efficacy under lysosomal conditions and in serum environments. Another notable patent involves humanized antibodies against CEACAM1. This invention provides humanized antibodies that specifically bind to human CEACAM1 molecules, featuring human-to-murine back-mutations in non-CDR variable regions. The patent also includes pharmaceutical compositions containing these antibodies and methods for their use in treating and diagnosing cancer and other conditions.

Career Highlights

Tehila has worked with several companies throughout her career, including Protalix Ltd. and Famewave Ltd. Her experience in these organizations has allowed her to develop and refine her innovative ideas in protein therapeutics.

Collaborations

Tehila has collaborated with notable colleagues, including Yair Sapir and Ilana Mandel, who have contributed to her research and development efforts.

Conclusion

Tehila Ben-Moshe is a distinguished inventor whose work in protein therapeutics has the potential to significantly impact medical treatments. Her innovative patents and collaborations highlight her commitment to advancing healthcare solutions.