The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 30, 2022
Filed:
Dec. 02, 2019
Applicant:
Famewave Ltd., Rehovot, IL;
Inventors:
Tehila Ben-Moshe, Koranit, IL;
Yair Sapir, Manof, IL;
Ilana Mandel, Carmiel, IL;
Gal Markel, Ramat Gan, IL;
Jacob Schachter, Givataim, IL;
Rona Ortenberg, Yokne'am Illit, IL;
Francis Joseph Carr, Aberdeenshire, GB;
Robert George E. Holgate, Royston, GB;
Timothy David Jones, Babraham, GB;
Assignee:
FAMEWAVE LTD., Rehovot, IL;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); C12N 15/62 (2006.01); A61K 39/395 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01); A61K 35/17 (2015.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3007 (2013.01); A61K 39/39558 (2013.01); C12N 15/62 (2013.01); G01N 33/57492 (2013.01); A61K 35/17 (2013.01); A61K 45/06 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); A61K 2039/545 (2013.01); C07K 16/2803 (2013.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/567 (2013.01); C07K 2317/73 (2013.01); C07K 2317/90 (2013.01); C07K 2317/92 (2013.01); G01N 2333/70503 (2013.01);
Abstract
Humanized antibodies, capable of specific binding to human CEACAM1 molecules containing human-to-murine back-mutations in non-CDR variable regions, and their encoding polynucleotide sequences are provided. Pharmaceutical compositions comprising these antibodies as well as methods of their use in treating and diagnosing cancer and other conditions are also provided.