Company Filing History:
Years Active: 2014-2019
Title: Taotao Zou: Innovator in DNA Targeting and Cancer Treatment
Introduction
Taotao Zou is a prominent inventor based in Hong Kong, CN. He has made significant contributions to the fields of molecular biology and oncology through his innovative research and patented methods. With a total of 3 patents, Zou's work focuses on targeting mismatched DNA and developing treatments for cancer.
Latest Patents
One of Zou's latest patents is titled "Method of targeting mismatched DNA using d8 square planar metal complexes." This patent discloses methods that utilize square planar metal complexes containing tridentate π-conjugated ligands and ancillary ligands, such as N-heterocyclic carbenes or di-phosphine ligands, to effectively target mismatched DNA. The targeting of mismatched DNA can be monitored by observing differences in emission enhancement of metal complexes towards both mismatched and matched DNA. Additionally, the method involves measuring the heat release from isothermal titration calorimetry (ITC) when complexes bind to mismatch DNA, as well as the significant increase in melting temperature of the mismatched DNA after the addition of these complexes.
Another notable patent by Zou is the "Method of using binuclear gold (I) compounds for cancer treatment." This patent provides a method for treating cancer through the administration of binuclear gold(I) compounds to patients in need. The pharmaceutical compounds exhibit anti-cancer activity, including the induction of cell death, inhibition of cellular proliferation, inhibition of thioredoxin reductase activity, and suppression of tumor growth in vivo.
Career Highlights
Taotao Zou is affiliated with The University of Hong Kong, where he conducts his research and develops his innovative methods. His work has garnered attention in the scientific community for its potential applications in medical treatments and diagnostics.
Collaborations
Zou collaborates with esteemed colleagues, including Chi Ming Che and Sin Ki Fung, who contribute to his research endeavors and enhance the impact of his inventions.
Conclusion
Taotao Zou is a distinguished inventor whose work in targeting mismatched DNA and cancer treatment showcases his commitment to advancing scientific knowledge and improving healthcare outcomes. His innovative patents reflect a dedication to addressing critical challenges in molecular biology and oncology.