The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2014

Filed:

Nov. 13, 2013
Applicant:

University of Hong Kong, Hong Kong, CN;

Inventors:

Chi Ming Che, Hong Kong, CN;

Taotao Zou, Hong Kong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/555 (2006.01); C07F 1/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein is a method of synthesis of Au(III)-NHC complexes, a pharmaceutical composition comprises thereof. Also provided herein are the methods for the treatment and prevention of cancer/tumor in patients in need thereof by the administration of the Au(III)-NHC complexes. Also provided is method of detecting thiol in a biological system. The Au(III)-NHC complexes possess anticancer activity such as the induction of cell death, inhibition of cellular proliferation, inhibition of thioredoxin reductase activity, and inhibition of tumor growth in vivo.


Find Patent Forward Citations

Che, Chi. (2014). Gold(iii) complexes containing n-heterocyclic carbene ligand, synthesis, and their applications in cancer treatment and thiol detection (U.S. Patent No. 8828984). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8828984

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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