Location History:
- Ashkelon, IL (2002 - 2008)
- Rehovot, IL (2002 - 2010)
Company Filing History:
Years Active: 2002-2010
Title: Tanya Goncharov: Innovator in Protein Modulation
Introduction
Tanya Goncharov is a prominent inventor based in Ashkelon, Israel. She has made significant contributions to the field of protein modulation, holding a total of 7 patents. Her work focuses on the interaction of proteins with FAS receptors and caspase-8, which are crucial in various cellular processes.
Latest Patents
One of her latest patents involves modulators of the function of FAS receptors and other proteins. This invention provides proteins capable of modulating or mediating the FAS receptor ligand or TNF effect on cells carrying the FAS receptor or p55 receptor. These proteins achieve this by binding or interacting with MORT-1 protein, which in turn binds to the intracellular domain of the FAS receptor or to another protein, TRADD, which binds to the p55 receptor. Additionally, her patent includes peptide inhibitors that interfere with the proteolytic activity of MORT-1-binding proteins that possess proteolytic activity, along with a method for designing them. Another significant patent focuses on caspase-8 interacting proteins, providing polypeptides that bind to caspase-8, along with the production and use of such polypeptides, DNA encoding them, and vectors and host cells containing this DNA.
Career Highlights
Tanya has established herself as a leading figure in her field through her innovative research and development efforts. She is currently associated with Yeda Research and Development Co. Ltd., where she continues to advance her work in protein modulation.
Collaborations
Throughout her career, Tanya has collaborated with notable colleagues, including David Wallach and Mark Boldin. These partnerships have further enriched her research and contributed to her success as an inventor.
Conclusion
Tanya Goncharov's contributions to the field of protein modulation are noteworthy, and her innovative patents reflect her expertise and dedication. Her work continues to impact the scientific community and advance our understanding of protein interactions.