The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 21, 2010
Filed:
Sep. 18, 2006
David Wallach, Rehovot, IL;
Mark Boldin, Rehovot, IL;
Tanya Goncharov, Rehovot, IL;
Yury V. Golstev, Rehovot, IL;
David Wallach, Rehovot, IL;
Mark Boldin, Rehovot, IL;
Tanya Goncharov, Rehovot, IL;
Yury V. Golstev, Rehovot, IL;
Yeda Research and Development Co. Ltd., Rehovot, IL;
Abstract
The present invention provides proteins capable of modulating or mediating the FAS receptor ligand or TNF effect on cells carrying FAS receptor or p55 receptor by binding or interacting with MORT-1 protein, which in turn binds to the intracellular domain of the FAS receptor or to another protein TRADD which binds to the p55 receptor. In addition, peptide inhibitors that interfere with the proteolytic activity of MORT-1-binding proteins having proteolytic activity are provided, as well as a method of designing them.