Takeshi Harada

Title: The Innovations of Takeshi Harada

Introduction

Takeshi Harada is a prominent inventor based in San Jose, CA, known for his contributions to the field of nanopore technology. With a total of 2 patents, he has made significant strides in enhancing the capabilities of sequencing chips.

Latest Patents

One of his latest patents is titled "Removing and reinserting protein nanopores in a membrane using osmotic imbalance." This invention provides techniques for replacing nanopores within a nanopore-based sequencing chip. By introducing an osmotic imbalance between the external reservoir and the well chamber of a lipid bilayer membrane, the membrane changes shape, allowing for the ejection of a nanopore. A second electrolyte solution is then added to restore the membrane shape and insert replacement nanopores without damaging the membrane.

Another notable patent is "Systems and methods for self-limiting protein pore insertion in a membrane." This patent describes systems and methods for inserting a single pore into a membrane using a stepped or ramped voltage waveform. The voltage is carefully controlled to minimize the risk of membrane damage while allowing sufficient time for the pores to be inserted.

Career Highlights

Takeshi Harada is currently employed at Roche Sequencing Solutions, Inc., where he continues to innovate in the field of sequencing technology. His work has been instrumental in advancing the capabilities of nanopore sequencing, which is crucial for various applications in genomics.

Collaborations

Throughout his career, Harada has collaborated with notable colleagues, including Geoffrey A. Barrall and Jason Komadina. These collaborations have further enriched his research and development efforts in nanopore technology.

Conclusion

Takeshi Harada's contributions to nanopore technology and his innovative patents have positioned him as a key figure in the field. His work at Roche Sequencing Solutions, Inc. continues to pave the way for advancements in sequencing technologies.