Location History:
- Kanagawa, JP (2014)
- Yokohama, JP (2012 - 2015)
Company Filing History:
Years Active: 2012-2015
Title: Takatsugu Kobayashi: Innovator in Non-Natural Amino Acid Incorporation
Introduction
Takatsugu Kobayashi is a prominent inventor based in Yokohama, Japan. He has made significant contributions to the field of biochemistry, particularly in the area of non-natural amino acids. With a total of 5 patents to his name, Kobayashi's work has the potential to revolutionize protein engineering.
Latest Patents
Kobayashi's latest patents include a mutant pyrrolysyl-tRNA synthetase and a method for the production of proteins that incorporate non-natural amino acids. His innovative method allows for the incorporation of a lysine derivative, specifically an N-benzyloxycarbonyl-lysine (Z-Lys) derivative, into proteins in a site-specific manner. This method utilizes a mutant pyrrolysyl-tRNA synthetase with specific amino acid substitutions to enhance the binding site for pyrrolysine. Additionally, he has developed a DNA construct that synthesizes a suppressor tRNA, which is crucial for producing proteins that incorporate non-natural amino acids.
Career Highlights
Kobayashi is affiliated with Riken Corporation, a leading research institution in Japan. His work at Riken has allowed him to collaborate with other esteemed scientists and contribute to groundbreaking research in protein synthesis and engineering.
Collaborations
Some of his notable coworkers include Shigeyuki Yokoyama and Kensaku Sakamoto. Their collaborative efforts have further advanced the understanding and application of non-natural amino acids in protein engineering.
Conclusion
Takatsugu Kobayashi's innovative work in the field of biochemistry, particularly in the incorporation of non-natural amino acids, showcases his significant contributions to science. His patents and research have the potential to impact various applications in biotechnology and medicine.