Fenton, MO, United States of America

Susan C Howard


Average Co-Inventor Count = 6.4

ph-index = 3

Forward Citations = 92(Granted Patents)


Company Filing History:


Years Active: 1990-2005

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8 patents (USPTO):Explore Patents

Title: Innovations of Susan C. Howard: A Pioneer in Matrix Metalloproteinase Research

Introduction

Susan C. Howard, based in Fenton, MO, has made notable contributions to the field of biochemistry with her eight patents. Her work primarily focuses on matrix metalloproteinases, enzymes involved in the degradation of various components of the extracellular matrix. Susan's inventions aim to provide therapeutic solutions for conditions tied to these enzymes, such as osteoarthritis.

Latest Patents

One of her latest patents is a method of changing the conformation of a matrix metalloproteinase. This innovative invention introduces a compound capable of inhibiting matrix metalloproteinases, detailing specific structural variations and the implications for treating osteoarthritis. Additionally, she holds a patent for an aromatic sulfone hydroxamic acid metalloprotease inhibitor, which is a treatment process that effectively targets certain MMP enzymes (MMP-2, MMP-9, and MMP-13) while exhibiting significantly less inhibition of MMP-1. This selective activity opens new avenues for therapeutic development, highlighting her significant contributions to pharmaceutical chemistry.

Career Highlights

Throughout her career, Susan has worked with prominent organizations such as Pharmacia Corporation and the Monsanto Company. Her professional journey reflects a dedication to innovation in therapeutic approaches, particularly in the area of enzyme inhibition and its applications in medical treatments.

Collaborations

In her research, Susan has collaborated with colleagues such as Gary A. DeCrescenzo and Joseph J. McDonald. These collaborations have fostered an environment of innovation and have been instrumental in the development of her patented technologies.

Conclusion

Susan C. Howard exemplifies the essence of innovation in the field of biochemistry. With eight patents to her name, her ongoing research into matrix metalloproteinases continues to pave the way for new treatments in osteoarthritis and related conditions. Her career not only reflects her scientific prowess but also underscores the importance of collaboration in driving medical advancements.

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