The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 22, 2005

Filed:

Jul. 12, 2000
Applicants:

William C. Stallings, Wildwood, MO (US);

Huey S. Shieh, St. Louis, MO (US);

Susan C. Howard, Fenton, MO (US);

Gary A. Decrescenzo, Dardeene Prairie, MO (US);

Joseph J. Mcdonald, Wildwood, MO (US);

Inventors:

William C. Stallings, Wildwood, MO (US);

Huey S. Shieh, St. Louis, MO (US);

Susan C. Howard, Fenton, MO (US);

Gary A. DeCrescenzo, Dardeene Prairie, MO (US);

Joseph J. McDonald, Wildwood, MO (US);

Assignee:

Pharmacia Corporation, St. Louis, MO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K031/5377 ; C07D295/14 ; A61P019/02 ;
U.S. Cl.
CPC ...
Abstract

The present invention provides a matrix metalloproteinase inhibiting compound having structure (VIII) or a salt, an enantiomer, a diastereomer, a racemate, or a tautomer thereof. In other embodiments, the present invention provides a method of changing the conformation of a matrix metalloproteinase, a method of inhibiting a matrix metal metalloproteinase, and a method of treating osteoarthritis.


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