Susan Babuka

Title: The Innovative Contributions of Susan Babuka

Introduction

Susan Babuka is a prominent inventor based in Oakland, CA. She has made significant contributions to the field of biotechnology, particularly in the purification and recovery of interferon-beta. With a total of 7 patents to her name, her work has had a substantial impact on pharmaceutical compositions and methods.

Latest Patents

Among her latest patents are innovative methods for the purification and recovery of interferon-beta (IFN-β). One notable method involves precipitating substantially purified IFN-β or its variants and then dissolving them in a guanidine hydrochloride (HCl) solution. This process allows for the renaturation of the protein through dilution with a suitable buffer. Additionally, she has developed HSA-free formulations of interferon-beta, which are stabilized pharmaceutical compositions that maintain a low-ionic-strength formulation at a pH of about 3.0 to 5.0. These advancements are crucial for enhancing the solubility of IFN-β in pharmaceutical applications.

Career Highlights

Throughout her career, Susan has worked with notable companies such as Novartis Vaccines & Diagnostics and Chiron Corporation. Her experience in these organizations has contributed to her expertise in the field of biotechnology and pharmaceuticals.

Collaborations

Susan has collaborated with esteemed colleagues, including Bret A. Shirley and Bao-lu Chen. These partnerships have further enriched her research and development efforts.

Conclusion

Susan Babuka's innovative work in the purification and recovery of interferon-beta showcases her significant contributions to biotechnology. Her patents and collaborations reflect her dedication to advancing pharmaceutical science.