The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 13, 2008
Filed:
Feb. 18, 2005
Bret A. Shirley, Waltham, MA (US);
Susan Babuka, Oakland, CA (US);
Bao-lu Chen, San Ramon, CA (US);
Maninder Hora, Danville, CA (US);
Minna Choe, Danville, CA (US);
Melanie Tellers, Cranford, NJ (US);
Bret A. Shirley, Waltham, MA (US);
Susan Babuka, Oakland, CA (US);
Bao-Lu Chen, San Ramon, CA (US);
Maninder Hora, Danville, CA (US);
Minna Choe, Danville, CA (US);
Melanie Tellers, Cranford, NJ (US);
Novartis Vaccines and Diagnostics, Inc., Emeryville, CA (US);
Abstract
Stabilized pharmaceutical compositions comprising substantially monomeric interferon-beta (IFN-β) and methods useful in their preparation are provided. The compositions comprise the IFN-β solubilized in a low-ionic-strength formulation that maintains the composition at a pH of about 3.0 to about 5.0. Methods for preparing these compositions, and for increasing solubility of IFN-β in pharmaceutical compositions, are provided.