Sunil Bhakta

Title: **Innovator Spotlight: Sunil Bhakta**

Introduction

Sunil Bhakta is a notable inventor based in San Ramon, CA, who has made significant contributions to the field of biotechnology. With a portfolio of five patents, his work often focuses on the engineering of antibodies, which are crucial in therapeutic applications.

Latest Patents

Among his latest innovations are patents related to cysteine engineered antibodies and conjugates. These antibodies are created by mutagenizing the nucleic acid sequence of a parent antibody and substituting certain amino acid residues with cysteine. The resultant cysteine engineered antibodies can include a free cysteine amino acid in either the heavy chain or light chain. The process involves expressing and isolating these antibodies, with highly reactive cysteine engineered antibodies identified by the PHESELECTOR assay. Moreover, these isolated antibodies have the potential to be covalently attached to various labels or drug moieties, enhancing their application in medical diagnostics and therapeutics.

Career Highlights

Sunil Bhakta has established himself as a key player in the biotech industry through his work at Genentech, Inc. His innovative contributions to antibody engineering have been instrumental in advancing therapeutic options for various medical conditions.

Collaborations

Throughout his career, Sunil has collaborated with notable colleagues, including Jagath Reddy Junutula and Hans Erickson. These partnerships have played a crucial role in honing his research and expanding the horizons of antibody technology.

Conclusion

With a firm foundation in biotechnological innovations and a strategic approach to antibody engineering, Sunil Bhakta continues to push the boundaries of science. His work not only reflects his dedication to the field but also paves the way for future advancements in therapeutic applications.