Location History:
- Hawthorne, CA (US) (2021 - 2024)
- Los Angeles, CA (US) (2024)
Company Filing History:
Years Active: 2021-2025
Title: Innovations of Steven J Jonas
Introduction
Steven J Jonas is a notable inventor based in Hawthorne, California, with a remarkable portfolio of six patents. His work primarily focuses on advanced methods for intracellular delivery of biomolecular cargo, which has significant implications in the fields of biotechnology and medicine.
Latest Patents
One of his latest patents is a high-throughput system and method for the temporary permeabilization of cells using lipid bilayers. This microfluidic device is designed to process cells for the intracellular delivery of molecules or other cargo. The device features one or more microchannels that are fluidically coupled to an inlet, allowing for the introduction of a solution containing the cells and the desired cargo. Each microchannel includes constriction regions with lipid bilayers, enhancing the efficiency of the delivery process. This technology is particularly applicable for delivering gene-editing molecules into cells.
Another significant patent involves guided magnetic nanostructures for targeted and high-throughput intracellular delivery. This method utilizes magnetic nanostructures, such as nanospears and nanostars, to transport biomolecular cargo into cells. By applying an external magnetic field, these nanostructures can be maneuvered into contact with the cells, facilitating the delivery of various biological constructs, including DNA plasmids and gene-editing tools.
Career Highlights
Throughout his career, Steven J Jonas has contributed to significant advancements in the field of cellular delivery systems. He has worked with prestigious institutions, including the University of California and Harvard College, where he has honed his expertise in microfluidics and nanotechnology.
Collaborations
Steven has collaborated with esteemed colleagues such as Paul S Weiss and Xiaobin Xu, further enhancing the impact of his research and innovations.
Conclusion
Steven J Jonas is a pioneering inventor whose work in intracellular delivery systems is shaping the future of biotechnology. His innovative patents and collaborations reflect his commitment to advancing scientific knowledge and technology.