Stephen James Burke, an inventive mind based in Mount Airy, MD, has made significant strides in the field of biochemistry and immunology. With a total of two patents to his name, he showcases a commitment to advancing scientific knowledge and technology through his innovative ideas.

Latest Patents

Stephen's latest patents reflect his expertise in the development of Multi-chain polypeptide-containing tri-specific binding molecules. These Tri-Specific Binding Molecules are multi-chain polypeptide structures with three Binding Domains, enabling coordinated binding to three distinct epitopes. The flexibility of the Binding Domains allows them to target any combination of epitopes, which can belong to the same antigen or different antigens. Notably, one of the epitopes is designed to bind to CD3, another to CD8, while the third targets a Disease-Associated Antigen. This invention also includes a novel ROR1-binding antibody along with its derivatives and potential applications.

Career Highlights

Currently, Stephen serves as a key innovator at Macrogenics, Inc., a company renowned for its cutting-edge therapies in oncology and immunology. His contributions to the field have been instrumental in the advancement of therapeutic solutions aimed at complex diseases.

Collaborations

Throughout his career, Stephen has collaborated with talented professionals, including Leslie Sydnor Johnson and Ling Ling Huang. These collaborations highlight the synergy needed to push the boundaries of scientific research and development.

Conclusion

Stephen James Burke exemplifies the dedication and ingenuity of modern inventors in the realm of biochemistry. His work in creating tri-specific binding molecules is a testament to the power of innovation in tackling significant health challenges. As he continues to develop groundbreaking technologies, Stephen remains a notable figure in the pursuit of advancing medical science.

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