The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2025
Filed:
Jun. 22, 2022
Applicant:
Macrogenics, Inc., Rockville, MD (US);
Inventors:
Krishnan Sampathkumar, Rockville, MD (US);
Yan Zhou, Rockville, MD (US);
Stephen James Burke, Rockville, MD (US);
Assignee:
Macrogenics, Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/12 (2006.01); A61K 47/26 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39591 (2013.01); A61K 47/12 (2013.01); A61K 47/26 (2013.01); C07K 16/2818 (2013.01); C07K 2317/24 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present disclosure is provides pharmaceutical compositions, for storage and administration, comprising a human PD-1 ('hPD-1') antibody (“retifanlimab”) and buffering agents. The disclosure further provides containers and kits comprising such pharmaceutical compositions. The disclosure further provides the use of such pharmaceutical compositions, containers, and kits containing retifanlimab in the treatment of a cancer, and in certain aspects treatment of a cancer expressing PD-L1.