Houston, TX, United States of America

Sophia Yang Tsai


Average Co-Inventor Count = 4.7

ph-index = 4

Forward Citations = 25(Granted Patents)


Company Filing History:


Years Active: 1998-2010

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8 patents (USPTO):Explore Patents

Title: An Overview of Inventor Sophia Yang Tsai - Pioneering Innovations in Biomedical Research

Introduction: Sophia Yang Tsai, based in Houston, TX, is an accomplished inventor known for her groundbreaking contributions to biomedical research. With a remarkable portfolio of 8 patents, she has significantly advanced our understanding of molecular signaling pathways and therapeutic applications.

Latest Patents: Among her most recent innovations is her patent on the modulation of the hedgehog-mediated signaling pathway. This invention outlines transcription factors associated with the hedgehog signaling pathway, regulated by dephosphorylation through phosphatases. It also presents hedgehog response elements (HRE) that interact with these dephosphorylated transcription factors, alongside methods to identify compounds that inhibit phosphatases. Additionally, her work includes methods for treating tumors by modulating transcription factor phosphorylation. Another notable patent involves gene switch systems that employ regulators exhibiting decreased dimerization. This novel inducible expression system is characterized by an undetectable biological effect in the absence of an inducer, yet demonstrates efficient inducibility when the inducer is present.

Career Highlights: Sophia has worked with prominent institutions such as Baylor College of Medicine, where she has made significant strides in her research. Her innovative mindset and dedication have positioned her as a leading figure in her field, reflecting the importance of her work in combating diseases.

Collaborations: Throughout her career, Sophia has collaborated with esteemed colleagues, including Ming-Jer Tsai and Bert W O'Malley. These collaborations have enriched her research and have fostered advancements in the understanding of complex biological processes.

Conclusion: Sophia Yang Tsai is a remarkable inventor whose contributions to the field of biomedical research continue to pave the way for new therapeutic strategies. Her patents reflect a commitment to innovation and the drive to enhance our understanding of molecular pathways, ultimately benefiting healthcare and research.

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