Company Filing History:
Years Active: 2019-2020
Title: Innovations by Sin Ki Fung in Cancer Treatment
Introduction
Sin Ki Fung is a notable inventor based in Hong Kong, CN. He has made significant contributions to the field of cancer treatment through his innovative research and patented inventions. With a total of 2 patents, his work focuses on the development of platinum complexes that have potential applications in oncology.
Latest Patents
One of Sin Ki Fung's latest patents involves the creation of Platinum (II) complexes containing N-heterocyclic carbene ligands and pincer ligands. This patent outlines a method for synthesizing these Pt(II) complexes, which can be used in pharmaceutical compositions for cancer treatment. The invention also includes methods for treating and preventing cancer in patients through the administration of these complexes. Additionally, it provides a method for detecting the Pt(II) complex within biological systems. The anticancer activity of these complexes is notable, as they induce cell death, inhibit cellular proliferation, and prevent tumor growth in vivo.
Another significant patent focuses on the method of targeting mismatched DNA using d8 square planar metal complexes. This invention discloses methods for utilizing square planar metal complexes that contain tridentate π-conjugated ligands and ancillary ligands of N-heterocyclic carbene or di-phosphine to specifically target mismatched DNA. The targeting can be monitored through various methods, including emission enhancement differences between mismatched and matched DNA, heat release from isothermal titration calorimetry (ITC), and increases in the melting temperature of mismatched DNA upon complex addition.
Career Highlights
Sin Ki Fung is affiliated with The University of Hong Kong, where he conducts his research and develops his innovative ideas. His work has garnered attention in the scientific community, particularly for its implications in cancer therapy.
Collaborations
Sin Ki Fung collaborates with esteemed colleagues, including Chi Ming Che and Tian Feng Chen, who contribute to his research endeavors and enhance the impact of his inventions.
Conclusion
Sin Ki Fung's innovative work in the field of cancer treatment through his patented inventions demonstrates his commitment to advancing medical science. His contributions have the potential to significantly impact the way cancer is treated and understood.