Taipei, Taiwan

Shu-Yi Lin

USPTO Granted Patents = 9 

 


Average Co-Inventor Count = 2.8

ph-index = 2

Forward Citations = 24(Granted Patents)


Location History:

  • Taipei County, TW (2010 - 2013)
  • Hsinchu, TW (2012 - 2013)
  • Miaoli County, TW (2015)
  • Taipei, TW (2009 - 2023)

Company Filing History:


Years Active: 2009-2023

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9 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Shu-Yi Lin

Introduction

Shu-Yi Lin is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of chemistry, particularly in the synthesis of complex compounds and therapeutic compositions. With a total of 9 patents to his name, Lin's work has the potential to impact various medical applications, especially in cancer treatment.

Latest Patents

One of Lin's latest patents focuses on methods of making high enantioselective secondary alcohols. This innovative process involves the synthesis of compound OBI-3424 in both R-form and S-form products. The R-form compound OBI-3423 was synthesized with an overall yield of 48% from compound OBI-3424-5 by installing a labile phosphate motif at a later stage. The stereochemistry is established through a five-step chemo-enzyme combination synthesis, achieving 99% optical purity. Subsequently, the S-form compound OBI-3424 is prepared, improving the overall yield to 54% from compound OBI-3424-5, with a four-step combination of chemo-enzyme synthesis also yielding excellent optical purity of 99%.

Another significant patent by Lin encompasses immunogenic and therapeutic glycan compositions. This disclosure includes Globo series antigens such as SSEA-4, Globo H, or SSEA-3 glycoconjugates, along with therapeutic adjuvants like OBI-821 or OBI-834. These compositions are designed to treat proliferative diseases, including cancer. The therapeutic conjugates consist of an antigen linked to a carrier, and they are envisioned to act as cancer vaccines, enhancing the body's immune response against abnormal cells.

Career Highlights

Throughout his career, Shu-Yi Lin has worked with notable organizations, including Obi Pharma Inc. and the National Health Research Institutes. His work in these institutions has allowed him to advance his research and contribute to the development of innovative therapeutic solutions.

Collaborations

Lin has collaborated with esteemed colleagues such as Shiuh-Jer Huang and Guang-Ling He. These partnerships have fostered a collaborative environment that enhances the research and development of new inventions.

Conclusion

Shu-Yi Lin's innovative contributions to the field of chemistry and his dedication to developing therapeutic solutions highlight his importance as an inventor. His work continues to pave the way

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