The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Feb. 18, 2014
Applicant:

National Health Research Institutes, Miaoli County, TW;

Inventor:

Shu-Yi Lin, Miaoli County, TW;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 33/24 (2006.01); A61K 47/34 (2006.01); A61K 9/51 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/34 (2013.01); A61K 9/5146 (2013.01); A61K 33/24 (2013.01); A61K 47/48207 (2013.01); A61K 47/48215 (2013.01); A61K 47/48238 (2013.01); A61K 47/48853 (2013.01);
Abstract

A caged platinum nanocluster complex is disclosed. The complex comprises (a) an amine-terminated dendrimer; and (b) a platinum nanocluster comprising platinum oxides, the platinum nanocluster being confined inside of the amine-terminated dendrimer. The complex exhibits cytotoxicity to cancer cells. A double-caged platinum nanocluster complex is also disclosed, which comprises polyethylene glycol (PEG) coated on the surface of a dendrimer caged platinum nanocluster complex. The double-caged caged platinum nanocluster complex comprises pH-sensitive bonds on the surface thereof. Also disclosed are methods of preparing and using the same.


Find Patent Forward Citations

Loading…