Shu-Hui Liu

Title: Shu-Hui Liu: Innovative Patents in Biomedical Research and Therapeutics

Introduction:

Shu-Hui Liu, a resident of Redwood City, CA, is an accomplished inventor and researcher in the field of biomedical sciences. With a total of 13 patents to his name, Liu has made significant contributions to the development of antibody-based therapies for various medical conditions, particularly in the realm of cancer treatment. This article explores his latest patents, career highlights, collaborations, and overall contributions to the field.

Latest Patents:

Liu's recent patents showcase his expertise in developing antibodies and engineered polypeptide conjugates for targeted therapies:

1. Antibodies specific for Trop-2 and their uses:

This patent focuses on the discovery and development of antibodies that selectively bind to trophoblast cell-surface antigen-2 (Trop-2). These antibodies have potential applications in the treatment of different types of cancers, including colon, esophageal, gastric, head and neck, lung, ovarian, and pancreatic cancer.

2. Engineered polypeptide conjugates and methods for making thereof using transglutaminase:

The second patent highlights Liu's work in creating engineered polypeptide conjugates, such as antibody-drug-conjugates and bispecific antibodies. These conjugates utilize acyl donor glutamine-containing tags and amine donor agents, offering novel therapeutic strategies in biocompatible polymer-based therapies for a range of medical conditions.

Career Highlights:

Throughout his career, Liu has made significant contributions to the field of biomedical sciences. His achievements include:

1. Pfizer Corporation:

Liu worked at Pfizer Corporation, a leading pharmaceutical company, where he harnessed his expertise in antibody-based therapies to advance drug discovery and development.

2. Rinat Neuroscience Corporation (a part of Pfizer):

Liu also contributed to the groundbreaking research and development efforts led by Rinat Neuroscience Corporation, a subsidiary of Pfizer, focused on novel therapeutics for neurological disorders.

Collaborations:

In his research endeavors, Liu has collaborated with esteemed colleagues such as Wei-Hsien Ho and Pavel Strop. These collaborations have fostered an environment of innovation and have led to groundbreaking advancements in the field of biomedical research.

Conclusion:

Shu-Hui Liu's commendable contributions to the field of biomedical sciences, specifically in the domains of antibody-based therapies and engineered polypeptide conjugates, showcase his expertise and dedication to advancing medical treatments. With his patents and collaborations, Liu has greatly impacted the development of precision medicine, particularly in the fight against cancer. His inventions hold the potential to improve patient outcomes and quality of life, making him a valuable asset to the medical and scientific community.