The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 17, 2021
Filed:
Sep. 07, 2018
Rinat Neuroscience Corp., South San Francisco, CA (US);
Shu-Hui Liu, Redwood City, CA (US);
Wei-Hsien Ho, Belmont, CA (US);
Pavel Strop, San Mateo, CA (US);
Magdalena Grazyna Dorywalska, Redwood City, CA (US);
Arvind Rajpal, San Francisco, CA (US);
David Louis Shelton, Oakland, CA (US);
Thomas-Toan Tran, San Jose, CA (US);
Rinat Neuroscience Corp., South San Francisco, CA (US);
Abstract
The present invention provides antibodies that specifically bind to trophoblast cell-surface antigen-2 (Trop-2). The invention further provides antibody conjugates comprising such antibodies, antibody encoding nucleic acids, and methods of obtaining such antibodies. The invention further relates to therapeutic methods for use of these antibodies and Trop-2 antibody conjugates for the treatment of a condition associated with Trop-2 expression (e.g., cancer), such as colon, esophageal, gastric, head and neck, lung, ovarian, or pancreatic cancer.