Company Filing History:
Years Active: 1999-2001
Title: Shijie Yao: Innovator in Cancer Treatment
Introduction
Shijie Yao is a notable inventor based in San Antonio, TX (US). He has made significant contributions to the field of cancer treatment through his innovative work on camptothecin derivatives. With a total of 3 patents to his name, Yao's inventions focus on developing novel compounds that can effectively combat cancer.
Latest Patents
One of Yao's latest patents is centered around highly lipophilic camptothecin derivatives. This invention relates to novel derivatives of camptothecin, particularly those with substitutions at the C-7 position or at one of the C-9, C-10, C-11, or C-12 positions. The invention also includes methods for using these compounds as Topoisomerase I inhibitors to treat patients with cancer. Additionally, it encompasses pharmaceutical formulations that consist of these novel compounds in solution or suspension with one or more pharmaceutical excipients or diluents. Another patent also focuses on highly lipophilic camptothecin derivatives, providing novel compounds, formulations, and methods for treating cancer patients. These compounds are characterized by their novel substitutions at the C-7 position of the camptothecin scaffold B-ring, being highly lipophilic, lactone stable, and potent antineoplastic agents that do not require metabolic activation.
Career Highlights
Shijie Yao is currently associated with Bionumerik Pharmaceuticals, Inc., where he continues to advance his research and development efforts in the pharmaceutical industry. His work is pivotal in creating effective treatments for cancer, showcasing his dedication to improving patient outcomes.
Collaborations
Yao collaborates with esteemed colleagues such as Frederick H Hausheer and Pavankumar Nv Petluru, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Shijie Yao's contributions to cancer treatment through his innovative patents highlight his role as a significant inventor in the pharmaceutical field. His work continues to pave the way for new therapeutic options for patients battling cancer.