Location History:
- Narashino, JP (2000 - 2012)
- Tokyo, JP (2016 - 2021)
- Kawasaki, JP (2022)
Company Filing History:
9 out of 1,281 
3 out of 23 
1 out of 373 
Years Active: 2000-2022
Title: Shigeto Fukushima: Innovator in Nucleic Acid Delivery Systems
Introduction
Shigeto Fukushima is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of nucleic acid delivery systems, holding a total of 10 patents. His innovative work focuses on improving the efficiency and effectiveness of delivering nucleic acids to target sites in patients.
Latest Patents
Fukushima's latest patents include a "Nucleic acid-loaded unit polyion complex." This invention describes a unit-type polyion complex designed for delivering nucleic acid to a target site in a patient. It comprises one or more molecules of a block copolymer featuring a poly(ethylene glycol) segment and a cationic poly(amino acid) segment. The total quantity of positive charges from the cationic poly(amino acid) segment is not offset by the negative charges from the nucleic acid. Additionally, the nucleic acid has a strand length of 10-50 bases, and the block copolymer has a binding constant (Ka) for the nucleic acid of 3.0 or more.
Another notable patent is the "Unit structure-type pharmaceutical composition for nucleic acid delivery." This composition includes a single nucleic acid, such as an antisense nucleic acid, electrostatically bound to a block copolymer with a cationic polyamino acid segment and a hydrophilic polymer chain segment. The negative charges of the nucleic acid are counterbalanced by the positive charges of the cationic polyamino acid segment, resulting in an electrically neutral or nearly electrically neutral pharmaceutical composition. The hydrophilic polymer chain segment enhances the blood retention capability of the nucleic acids.
Career Highlights
Fukushima has worked with esteemed institutions, including The University of Tokyo and Nanocarrier Co., Ltd. His research and innovations have significantly advanced the field of drug delivery systems, particularly in the area of nucleic acids.
Collaborations
He has collaborated with notable colleagues such as Kazunori Kataoka and Nobuhiro Nishiyama, contributing to the development of groundbreaking technologies in the pharmaceutical industry.
Conclusion
Shigeto Fukushima's work in nucleic acid delivery systems exemplifies the impact of innovative thinking in medicine. His patents and collaborations continue to influence the field, paving the way for future advancements in drug delivery
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.