The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 2010
Filed:
Feb. 08, 2006
Kazunori Kataoka, Tokyo, JP;
Keiji Itaka, Tokyo, JP;
Nobuhiro Nishiyama, Tokyo, JP;
Shigeto Fukushima, Narashino, JP;
Woo-dong Jang, Seoul, KR;
Kanjiro Miyata, Tokyo, JP;
Masataka Nakanishi, Tokyo, JP;
Shunsaku Asano, Tokyo, JP;
Naoki Kanayama, Wako, JP;
Kazunori Kataoka, Tokyo, JP;
Keiji Itaka, Tokyo, JP;
Nobuhiro Nishiyama, Tokyo, JP;
Shigeto Fukushima, Narashino, JP;
Woo-Dong Jang, Seoul, KR;
Kanjiro Miyata, Tokyo, JP;
Masataka Nakanishi, Tokyo, JP;
Shunsaku Asano, Tokyo, JP;
Naoki Kanayama, Wako, JP;
The University of Tokyo, Tokyo, JP;
Abstract
Disclosed is a composition for the delivery of nucleic acid to target cells or tissues, which comprises a polycationically charged polymer as a carrier of nucleic acid. The polycationically charged polymer is a polymer which may comprise a charged polymer segment having a main chain based on poly(amino acid), polysaccharide, polyester, polyether, polyurethane or vinyl polymer and having, as a side chain, a group of formula —NH—(CH)—(NH(CH))—NH(wherein a and e independently denote an integer of 1 to 5) which is connected to the main chain either directly or via a linker. The disclosed composition has low toxicity, and has a high efficiency in introducing nucleic acid into cells.