Shigeo Matsuda

This inventor holds 31 USPTO granted patents and 23 published patent applications, plus 4 CIPO patents and 5 EPO patents, primarily in Biodegradable Lipids. Top assignee: Alnylam Pharmaceuticals, Inc.. Active years: 2015-2025.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Shigeo Matsuda. Retrieved from https://idiyas.com/inventor/shigeo-matsuda

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 31 (Patent Applications = 23)

% Patents Active = 100.0

CIPO Patents = 4 (Patent Applications = 5)

EPO Patents = 5 (Patent Applications = 23)

Average Co-Inventor Count = 7.5

ph-index = 9

Forward Citations = 319(Granted Patents)

Company Filing History:

31 out of 466

Alnylam Pharmaceuticals, Inc.

patents

Years Active: 2015-2025

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Areas of Expertise:

Biodegradable Lipids

Modified RNA Agents

Oligonucleotide-Ligand Conjugates

Nucleic Acid Modifications

Chemical Modifications

iRNA Compositions

Strand Biased Improvement

Active Agent Delivery

Chirally-Enriched RNA

4'-C Position RNAi

Monomer Modifications

Cycloaddition Processes

31 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12364762 - Biodegradable lipids for the delivery of active agents (2025-07-22),

2. 12350338 - Biodegradable lipids for the delivery of active agents (2025-07-08),

3. 12343398 - Biodegradable lipids for the delivery of active agents (2025-07-01),

4. 12275938 - Modified RNA agents with reduced off-target effect (2025-04-14),

5. 12247203 - Modified RNA agents with reduced off-target effect (2025-03-11),

6. 12239709 - Biodegradable lipids for the delivery of active agents (2025-03-04),

7. 12173288 - Oligonucleotide-ligand conjugates and process for their preparation (2024-12-24),

8. 12173287 - Compositions and methods for improving strand biased (2024-12-24),

9. 11725207 - Serpina1 iRNA compositions and methods of use thereof (2023-08-15),

10. 11679158 - Biodegradable lipids for the delivery of active agents (2023-06-20),

11. 11633480 - Biodegradable lipids for the delivery of active agents (2023-04-25),

12. 11633479 - Biodegradable lipids for the delivery of active agents (2023-04-25),

13. 11612657 - Biodegradable lipids for the delivery of active agents (2023-03-28),

14. 11597932 - Chirally-enriched double-stranded RNA agents (2023-03-07),

15. 11590229 - Biodegradable lipids for the delivery of active agents (2023-02-28),

Title: Shigeo Matsuda: A Pioneer in Biodegradable Lipid Technologies

Introduction

Shigeo Matsuda, based in Cambridge, MA, is an accomplished inventor known for his significant contributions to the field of biodegradable lipid technologies. With an impressive portfolio comprising 26 patents, Matsuda's work primarily focuses on innovative delivery systems for therapeutic agents, particularly nucleic acids.

Latest Patents

Matsuda's latest patents showcase his cutting-edge research. One notable invention is the "Biodegradable lipids for the delivery of active agents." This invention introduces a cationic lipid with one or more biodegradable groups in its hydrophobic chain, designed to form lipid particles that effectively deliver active agents such as nucleic acids. Additionally, his patent titled "Oligonucleotide-ligand conjugates and process for their preparation" involves the creation of ligand conjugates of oligonucleotides, specifically using monosaccharides. These conjugates are valuable for the in vivo delivery of therapeutic oligonucleotides.

Career Highlights

Shigeo Matsuda is currently associated with Alnylam Pharmaceuticals, Inc., where he continues to innovate in the realm of medical and pharmaceutical technologies. His expertise in developing biodegradable delivery systems has propelled advancements in drug delivery and therapeutics.

Collaborations

Throughout his career, Matsuda has worked alongside notable colleagues, including Muthiah Manoharan and Kallanthottathil G Rajeev. Their collaborative efforts have further enhanced the impact of their research on lipid-based therapeutics.

Conclusion

In conclusion, Shigeo Matsuda is a leader in the field of biodegradable lipids, with a significant number of patents to his name. His contributions not only advance scientific knowledge but also have the potential to revolutionize the delivery of essential therapeutic agents.

Profile summary based on public USPTO records.