The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 07, 2023
Filed:
Dec. 21, 2018
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Muthiah Manoharan, Cambridge, MA (US);
Nate Taneja, Cambridge, MA (US);
Hartmut Ingo Jahns, Cambridge, MA (US);
Shigeo Matsuda, Cambridge, MA (US);
Klaus Charisse, Cambridge, MA (US);
Guo He, Cambridge, MA (US);
Jayaprakash K. Nair, Cambridge, MA (US);
Christopher Brown, Cambridge, MA (US);
Mark K. Schlegel, Cambridge, MA (US);
Vasant Jadhav, Cambridge, MA (US);
Martin Maier, Cambridge, MA (US);
Alnylam Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The present invention relates to a chirally-modified dsRNA agent capable of inhibiting the expression of a target gene. The sense and antisense strands of chirally-modified dsRNA agent independently or in combination comprises one or more site specific-site specific/position specific, chirally-modified internucleotide linkages.