Location History:
- Lexington, MA (US) (2014)
- Cambridge, MA (US) (2016 - 2023)
Company Filing History:
7 out of 3,923 
2 out of 123 
1 out of 443 
Years Active: 2014-2023
Title: Guo He: Innovator in Chirally-Enriched RNA Agents
Introduction
Guo He is a prominent inventor based in Cambridge, MA (US), known for his significant contributions to the field of biotechnology. With a total of 8 patents, he has made remarkable advancements in the development of chirally-modified RNA agents and selective estrogen receptor degraders.
Latest Patents
One of Guo He's latest patents is focused on chirally-enriched double-stranded RNA agents. This invention relates to a chirally-modified dsRNA agent capable of inhibiting the expression of a target gene. The sense and antisense strands of this chirally-modified dsRNA agent can independently or in combination comprise one or more site-specific, chirally-modified internucleotide linkages. Another notable patent involves benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders. This invention pertains to compounds of a specific formula that have potential therapeutic applications.
Career Highlights
Throughout his career, Guo He has worked with leading companies in the pharmaceutical industry, including Novartis AG and Astex Therapeutics Limited. His work in these organizations has allowed him to contribute to groundbreaking research and development in drug discovery and biotechnology.
Collaborations
Guo He has collaborated with several notable professionals in his field, including Heather Elizabeth Burks and Michael A Dechantsreiter. These collaborations have further enhanced his research and innovation capabilities.
Conclusion
Guo He is a distinguished inventor whose work in chirally-modified RNA agents and selective estrogen receptor degraders has made a significant impact in biotechnology. His contributions continue to advance the field and hold promise for future therapeutic applications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.