Culver City, CA, United States of America

Sherven Sharma

USPTO Granted Patents = 6 


 

Average Co-Inventor Count = 4.9

ph-index = 1

Forward Citations = 9(Granted Patents)


Location History:

  • Culver City, CA (US) (2014 - 2022)
  • Oakland, CA (US) (2019 - 2023)

Company Filing History:


Years Active: 2014-2023

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6 patents (USPTO):Explore Patents

Title: Sherven Sharma: Innovator in Cancer Treatment

Introduction

Sherven Sharma is a renowned inventor based in Culver City, California, recognized for his significant contributions to the field of cancer treatment through innovative therapeutic methodologies. With a total of six patents to his name, Sharma's work primarily focuses on enhancing cytokine delivery and improving cancer immunotherapy strategies.

Latest Patents

Among his latest patents is the invention of vault complexes for cytokine delivery. This groundbreaking invention details compositions of vault complexes comprising recombinant cytokine fusion proteins, which include a cytokine and a vault targeting domain. The method aims to effectively deliver these cytokines to target cells or subjects, with particular applications in treating cancers such as lung cancer.

Another notable patent developed by Sharma involves combination immunotherapy. This invention is anchored on the discovery that secondary lymphoid organ chemokine (SLC) can inhibit the growth of syngeneic tumors in vivo. The associated method entails administering a therapeutically effective amount of SLC to a mammal in conjunction with a checkpoint inhibitor, which may include monoclonal antibodies and small molecule inhibitors. Key checkpoint molecules referenced in the patent include CTLA-4, PD-1, and others, alongside SLC polypeptides and their variants.

Career Highlights

Sherven Sharma has worked with reputable institutions, including the University of California and the United States Government as represented by the Department of Veterans Affairs. These affiliations have positioned him in environments that fostered innovation and collaboration in scientific research pertinent to healthcare.

Collaborations

Throughout his illustrious career, Sharma has collaborated with distinguished colleagues such as Steven M Dubinett and Leonard H Rome. These partnerships have enriched his research endeavors, allowing for a collective pursuit of advancements in cancer treatment methodologies.

Conclusion

Sherven Sharma’s dedication to innovation in cancer treatment is evident through his patents and collaborative efforts. His work continues to pave the way for new therapeutic strategies, potentially transforming the landscape of cancer therapy for patients worldwide.

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