The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 01, 2019

Filed:

Sep. 05, 2016
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Leonard H. Rome, Los Angeles, CA (US);

Valerie A. Kickhoefer, Sherman Oaks, CA (US);

Sherven Sharma, Oakland, CA (US);

Steven M. Dubinett, Los Angeles, CA (US);

Isaac Yang, Los Angeles, CA (US);

Linda M. Liau, Los Angeles, CA (US);

Kathleen A. Kelly, Pacific Palisades, CA (US);

Jian Yang, Los Angeles, CA (US);

Upendra K. Kar, Oakland, CA (US);

Cheryl Champion, Greensboro, GA (US);

Janina Jiang, Los Angeles, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 38/17 (2006.01); A61K 38/19 (2006.01); A61K 9/50 (2006.01); C07K 14/00 (2006.01); C07K 14/77 (2006.01); A61K 38/45 (2006.01); A61K 47/64 (2017.01); A61K 47/69 (2017.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 9/5052 (2013.01); A61K 38/177 (2013.01); A61K 38/19 (2013.01); A61K 38/195 (2013.01); A61K 38/45 (2013.01); A61K 47/646 (2017.08); A61K 47/6925 (2017.08); C07K 14/00 (2013.01); C07K 14/77 (2013.01); C12Y 204/0203 (2013.01); A61K 2039/55516 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); A61K 2039/575 (2013.01); A61K 2039/6031 (2013.01); A61K 2039/6081 (2013.01); A61K 2039/64 (2013.01); A61K 2039/645 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C12N 2710/14043 (2013.01);
Abstract

The invention relates to compositions of vault complexes for use as adjuvants for stimulating a cellular immune response to an antigen, for example a tumor antigen, and methods of using the vault complexes in the treatment of diseases, such as cancer.


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