Location History:
- Madison, WI (US) (2002)
- Baltimore, MD (US) (2000 - 2011)
Company Filing History:
Years Active: 2000-2011
Title: Sean O'Herrin: Innovator in Immune Response Modulation
Introduction
Sean O'Herrin is a prominent inventor based in Baltimore, MD (US), known for his significant contributions to the field of immunology. With a total of 7 patents, O'Herrin has focused on developing innovative solutions that modify immune responses, which have potential applications in treating various disorders.
Latest Patents
O'Herrin's latest patents include groundbreaking work on cell compositions that comprise molecular complexes designed to modify immune responses. One of his notable inventions involves compositions that bind a molecular complex with high affinity for its cognate ligand to the surface of a cell. This technology utilizes extracellular domains of transmembrane heterodimeric proteins, particularly T cell receptors and major histocompatibility complex proteins, which can be covalently linked to immunoglobulin molecules. These molecular complexes are instrumental in detecting and regulating antigen-specific T cells and serve as therapeutic agents for disorders such as allergies, autoimmune diseases, tumors, infections, and transplant rejection. Another significant patent involves the use of multivalent chimeric peptide-loaded MHC/Ig molecules to detect, activate, or suppress antigen-specific T cell-dependent immune responses. This innovation enhances the effective affinity of soluble analogs of peptide/MHC molecules for their cognate ligands, demonstrating high specificity and affinity in binding to cells.
Career Highlights
O'Herrin is affiliated with The Johns Hopkins University, where he continues to advance research in immunology. His work has garnered attention for its potential to revolutionize treatments for immune-related conditions.
Collaborations
Throughout his career, O'Herrin has collaborated with esteemed colleagues, including Jonathan Schneck and Michael S. Lebowitz, contributing to a rich environment of innovation and research.
Conclusion
Sean O'Herrin's contributions to the field of immunology through his patents and research at The Johns Hopkins University highlight his role as a leading inventor in immune response modulation. His work promises to impact the treatment of various immune-related disorders significantly.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.