Company Filing History:
Years Active: 2023-2025
Title: Scott Loughhead: Innovator in Biomolecular Delivery
Introduction
Scott Loughhead is a notable inventor based in Watertown, MA (US). He has made significant contributions to the field of biomolecular delivery, holding three patents that focus on innovative methods for inducing tolerance and suppressing immune responses.
Latest Patents
One of his latest patents is titled "Intracellular delivery of biomolecules to induce tolerance." This invention provides methods for inducing tolerance and/or suppressing an immune response to an antigen by passing a cell suspension containing an anucleate cell through a constriction. The constriction deforms the cell, causing a perturbation that allows an antigen and/or tolerogenic factor to enter the cell. In some embodiments, the anucleate cell is delivered to an individual, and the antigen is processed in a tolerogenic environment to induce tolerance and/or suppress an immune response. Another significant patent is related to "Formulations of PBMCs." This application provides formulations of modified peripheral blood mononuclear cells (PBMCs), which include PBMCs comprising at least one antigen, such as a human papillomavirus (HPV) antigen, and a cryopreservation medium. In some cases, the PBMCs are conditioned by incubating them in the presence of an adjuvant.
Career Highlights
Scott Loughhead has worked with prominent companies in the biotechnology sector, including Stemcell Technologies Canada Inc. and Sqz Biotechnologies Company. His work has focused on advancing the understanding and application of biomolecular therapies.
Collaborations
Throughout his career, Scott has collaborated with notable professionals in the field, including Howard Bernstein and Armon R Sharei. These collaborations have contributed to the development of innovative solutions in biomolecular delivery.
Conclusion
Scott Loughhead is a distinguished inventor whose work in biomolecular delivery has the potential to significantly impact medical therapies. His patents reflect a commitment to advancing the field and improving patient outcomes.