Company Filing History:
2 out of 167 
1 out of 11 Years Active: 2022-2023
Title: Inventor Sanghwan Ko: Innovations in Antibody Therapeutics
Introduction
Sanghwan Ko is an influential inventor based in Seoul, South Korea, recognized for his contributions to the field of antibody therapeutics. With a total of two patents to his name, his work primarily revolves around optimizing antibody functions to enhance therapeutic efficacy and safety.
Latest Patents
1. **Fc-gamma receptor mutants**: This patent describes a polypeptide that includes an Fc-gamma receptor mutant optimized for selective binding to immunoglobulins. By substituting parts of the amino acid sequence of the Fc-gamma receptor, the invention aims to improve drug half-life in vivo, enhance detection and purification of immunoglobulins, and contribute to preventing organ transplant rejections or treating autoimmune diseases.
2. **Antibody Fc variants for increased blood half-life**: This patent details an Fc variant produced by modifying the amino acid sequence of the Fc domain of a human antibody. The invention encompasses a range of therapeutic, diagnostic, or laboratory reagents, focusing on maximizing the in vivo half-life of antibodies. This innovation is particularly valuable in cancer treatment, where the antibody or Fc fusion construct can target and eliminate cancer cells or interfere with specific antigens.
Career Highlights
Sanghwan Ko has made a significant impact in the field through his positions at notable institutions. He has been actively involved with Kookmin University and the Osong Medical Innovation Foundation, where his research has focused on novel therapeutic strategies.
Collaborations
Throughout his career, Sanghwan Ko has collaborated with esteemed colleagues, including Sang Taek Jung and Migyeong Jo. These partnerships have bolstered his research efforts and contributed to the advancement of innovative therapeutic solutions.
Conclusion
Sanghwan Ko's contributions to antibody therapeutics showcase his commitment to enhancing medical treatments through innovative inventions. His patents reflect a deep understanding of biochemistry and therapeutic application, promising significant advancements in the treatment of various diseases, particularly in the realm of cancer therapy.