The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2023
Filed:
Sep. 13, 2018
Applicant:
Kookmin University Industry Academy Cooperation Foundation, Seoul, KR;
Inventors:
Sang Taek Jung, Gyeonggi-do, KR;
Migyeong Jo, Gyeonggi-do, KR;
Sanghwan Ko, Seoul, KR;
Bora Hwang, Gyeonggi-do, KR;
Assignee:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C12N 5/00 (2006.01); C12N 15/00 (2006.01); C07K 16/46 (2006.01); G01N 33/68 (2006.01); C07K 14/735 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6857 (2013.01); C07K 14/70535 (2013.01); A61K 38/00 (2013.01); C07K 16/46 (2013.01); C07K 2319/31 (2013.01); C12N 5/00 (2013.01); C12N 15/00 (2013.01); G01N 33/53 (2013.01);
Abstract
The present disclosure relates to a polypeptide including an Fc-gamma receptor mutant. The Fc-gamma receptor mutant of the present disclosure is optimized by substituting a part of an amino acid sequence of an Fc-gamma receptor with a different amino acid sequence, so as to provide an excellent selective binding ability to immunoglobulins. Therefore, it can be usefully used for increasing in vivo half-life of drugs, detecting and purifying immunoglobulins, inhibiting organ transplant rejections, or preventing or treating autoimmune diseases.