Sandra Ross

Title: Innovative Contributions of Sandra Ross in Biotechnology

Introduction

Sandra Ross, an accomplished inventor based in Thousand Oaks, CA, has made significant strides in the field of biotechnology. With a total of two patents to her name, her innovative work primarily focuses on developing bispecific antibody constructs, which hold great promise for therapeutic applications.

Latest Patents

Among her latest patents, one notable invention is the "Bispecific antibody construct directed to MUC17 and CD3." This invention encompasses bispecific antibody constructs that feature a first domain binding to MUC17 and a second domain binding to the extracellular epitope of the human CD3ε chain, with the potential inclusion of a third domain characterized as a specific Fc modality. Additionally, this patent provides a polynucleotide encoding the antibody construct, a vector containing this polynucleotide, host cells expressing the construct, and a pharmaceutical composition comprising these elements.

Another significant patent is focused on "Antibody constructs for CLDN18.2 and CD3." This invention includes an antibody construct comprising a domain that binds to Claudin 18.2 (CLDN18.2) along with another domain that binds to CD3. The patent also presents a polynucleotide encoding this antibody construct, a vector with said polynucleotide, and a host cell transformed or transfected with the specified polynucleotide or vector. Furthermore, it outlines a process for producing the antibody construct, a medical use of the construct, and a kit that includes the antibody construct.

Career Highlights

Sandra Ross has worked with prominent companies in the biotechnology sector, notably Amgen Research GmbH in Munich and Amgen Inc. Her expertise in biomedical research has allowed her to remain at the forefront of innovative developments in the field.

Collaborations

Throughout her career, Sandra has collaborated with esteemed colleagues such as Christoph Dahlhoff and Claudia Blümel. These partnerships have contributed to her achievements and the successful development of groundbreaking therapeutic solutions.

Conclusion

Sandra Ross's innovative work in the realm of bispecific antibodies reflects her commitment to advancing medical science. Her patents not only showcase her exceptional inventiveness but also highlight the potential of her creations to influence the future of therapeutic interventions in cancer and other diseases.