The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 2023
Filed:
Aug. 02, 2019
Amgen Research (Munich) Gmbh, Munich, DE;
Amgen Inc., Thousand Oaks, CA (US);
Christoph Dahlhoff, Munich, DE;
Claudia Blümel, Munich, DE;
Johannes Brozy, Munich, DE;
Tobias Raum, Munich, DE;
Elisabeth Nahrwold, Munich, DE;
Tara Arvedson, Thousand Oaks, CA (US);
Irwin Chen, Thousand Oaks, CA (US);
Sandra Ross, Thousand Oaks, CA (US);
Julie Bailis, Thousand Oaks, CA (US);
AMGEN RESEARCH (MUNICH) GMBH, Munich, DE;
AMGEN INC., Thousand Oaks, CA (US);
Abstract
The present invention relates to an antibody construct comprising a domain which binds to Claudin 18.2 (CLDN18.2) and another domain which binds to CD3. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for producing the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.