Sailan Zhang

Title: The Innovative Contributions of Sailan Zhang

Introduction

Sailan Zhang is a prominent inventor based in Wuxi, China. He has made significant contributions to the field of enzyme engineering, particularly through his work on nitrile hydratase mutants. His innovative approach has led to advancements that could benefit industrial production processes.

Latest Patents

Sailan Zhang holds a patent for a mutant of nitrile hydratase. This patent discloses a mutant derived from nitrile hydratase, which exhibits remarkable enzymatic properties. The specific enzyme activity of the mutant, known as Nhase-A20V, is 128% of that of the wild enzyme. Additionally, this mutant has a half-life of about 10 minutes at 70° C., demonstrating thermal stability comparable to the wild enzyme. The mutant also shows improved tolerance to substrates and products, achieving a final yield of nicotinamide produced by whole-cell catalysis of 598 g/L. These properties indicate that the nitrile hydratase mutant Nhase-A20V has great potential for future industrial applications.

Career Highlights

Sailan Zhang is affiliated with Jiangnan University, where he continues to engage in research and development in enzyme engineering. His work has garnered attention for its practical applications in various industries.

Collaborations

Sailan Zhang has collaborated with notable colleagues, including Zhemin Zhou and Zhongmei Liu. Their combined expertise has contributed to the advancement of research in their field.

Conclusion

Sailan Zhang's innovative work in enzyme engineering, particularly with the nitrile hydratase mutant Nhase-A20V, showcases his significant contributions to the field. His research holds promise for enhancing industrial production processes and improving enzymatic applications.