S Derin Babacan

Title: Innovations in Imaging: The Contributions of S Derin Babacan

Introduction

S Derin Babacan is an accomplished inventor based in Champaign, IL (US). She has made significant contributions to the field of imaging, particularly in biological applications. With a total of 2 patents, her work focuses on enhancing resolution in microscopy techniques.

Latest Patents

One of her latest patents is titled "Sparse deconvolution spatial light microscopy in two and three dimensions." This invention provides methods and a computer program product for applying deconvolution to spatial light interference microscopy. It aims to enhance resolution beyond the diffraction limit in both two and three dimensions. By leveraging the sparsity properties of phase images, which are crucial in many biological imaging applications, Babacan's method allows for the recovery of fine structures that are often blurred by optics. This resolution improvement is vital for accurately monitoring dynamic activities over time. Experiments conducted with primary brain cells, including neurons and glial cells, have revealed new subdiffraction structures and motions. This innovative approach can be instrumental in studying vesicle transport in neurons, offering insights into dynamic cell functioning. Additionally, her method can flexibly incorporate a wide range of image models for various applications and is applicable across all imaging modalities that acquire complex field images.

Another notable patent is "White light diffraction tomography of unlabeled live cells." This invention outlines methods for obtaining a tomographic phase image of a specimen, whether in transmission or scatter. The specimen is illuminated by a temporally incoherent source, and the collected light is used to generate a scattered phase image in multiple axial planes. The scattered field is solved in wavevector space, and a derived instrument function is deconvolved to obtain specimen susceptibility in wavevector space. This susceptibility is then transformed to create a three-dimensional phase tomogram of the specimen.

Career Highlights

S Derin Babacan is affiliated with the University of Illinois, where she continues to advance her research in imaging technologies. Her work has garnered attention for its innovative approaches and practical applications in biological sciences.

Collaborations

She collaborates with notable colleagues, including Gabriel Popescu and Mustafa A H Mir, who contribute to her research endeavors.

Conclusion

S Derin Babacan's contributions to imaging technology, particularly in microscopy, are paving the way for new discoveries in biological research. Her innovative patents reflect her commitment to