This inventor holds 3 USPTO granted patents. Top assignees: Riken Corporation, The Yokohama Rubber Co., Ltd., Zeon Corporation. Active years: 2020-2021.
Company Filing History:
3 out of 887 
3 out of 2,770 
3 out of 1,290 
Years Active: 2020-2021
Title: Ryoko Orishimo: Innovator in Olefin Compound Production
Introduction
Ryoko Orishimo is a prominent inventor based in Wako, Japan. She has made significant contributions to the field of biochemistry, particularly in the production of olefin compounds. With a total of three patents to her name, her work focuses on enhancing the catalytic activity of enzymes used in industrial applications.
Latest Patents
Orishimo's latest patents include innovative methods for producing olefin compounds using variants of diphosphomevalonate decarboxylase (MVD). One of her notable inventions is a method that enables high productivity in olefin compound production. This method involves introducing mutations through amino acid substitutions at various sites of MVD to create multiple variants. The evaluation of these variants revealed that substituting serine at position 153 and threonine at position 209 with different amino acids significantly improved catalytic activity. Furthermore, additional substitutions at glycine position 152 further enhanced the catalytic efficiency of the variants.
Another patent focuses on the production of olefin compounds, where similar mutations were introduced into MVD. The results indicated that substituting glycine at a specific position with different amino acids led to improved catalytic activity. Additionally, further substitutions at arginine and threonine positions also resulted in high catalytic activity.
Career Highlights
Throughout her career, Ryoko Orishimo has worked with esteemed organizations such as Riken Corporation and Zeon Corporation. Her experience in these companies has allowed her to develop and refine her innovative approaches to enzyme engineering and olefin production.
Collaborations
Orishimo has collaborated with notable colleagues, including Tomokazu Shirai and Kazuhiro Takahashi. These partnerships have contributed to her research and the successful development of her patented technologies.
Conclusion
Ryoko Orishimo is a trailblazer in the field of biochemistry, particularly in the production of olefin compounds through innovative enzyme variants. Her patents reflect her dedication to enhancing catalytic activity, which has significant implications for industrial applications.