Company Filing History:
1 out of 11 
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1 out of 5,469 
Years Active: 2006-2018
Title: Ross Durland: Innovator in Aptamer Technology and Plasmid Purification
Introduction
Ross Durland is a prominent inventor based in The Woodlands, TX, recognized for his significant contributions to biotechnology through his innovative patents. With a total of three patents, Durland has made strides in areas like aptamer technology and plasmid purification.
Latest Patents
One of Durland's most recent patents is titled "Methods of X-aptamer generation and compositions thereof." This patent outlines a novel bead-based next-generation 'X-aptamer' selection scheme. This innovative method extends aptamer technology to incorporate X-modified bases, resulting in X-aptamers that can be synthesized at any position within their sequence through a split-pool strategy on individual beads. Additionally, it presents applications in various widely used DNA modifications, including monothioate and dithioate backbone substitutions. This advancement allows for chemical modifications to be introduced to any base in the aptamer sequence and the phosphate backbones.
Durland's second influential patent is focused on "Process and equipment for plasmid purification." This patent details a scalable alkaline lysis process designed to efficiently isolate large quantities of plasmid DNA from recombinant cells. The process ensures effective, controllable, and economical operations while maintaining a consistently low level of host chromosomal DNA in the final plasmid product. The inventiveness displayed in this patent involves a series of new unit operations and devices for cell resuspension, cell lysis, and neutralization.
Career Highlights
Throughout his career, Ross Durland has gathered significant experience at various companies, notably Valentis, Inc. His work has been instrumental in advancing the field of biotechnology through his innovative solutions and approaches.
Collaborations
Durland has collaborated with notable professionals such as Samuel Nochumson and Audrey Yu-Speight. These collaborations have further enriched his work and expanded the reach of his innovative patents within the biotechnology sector.
Conclusion
In summary, Ross Durland stands out as an influential inventor in the fields of aptamer technology and plasmid purification. His advanced methodologies and collaborative efforts have made a lasting impact on the biotechnology landscape, showcasing the importance of innovation in scientific research and development.