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For the Inventor, By the Inventor

Haifa, Israel

Rosa L Cyjon

USPTO Granted Patents = 17 

Average Co-Inventor Count = 3.8

ph-index = 7

Forward Citations = 109(Granted Patents)


Location History:

  • Haifa-Bay, IL (2016)
  • Haifa, IL (1993 - 2018)

Company Filing History:

goldMedal9 out of 10 
 
Concat, Ltd.
 patents
silverMedal5 out of 38 
 
Taro Pharmaceutical Industries Limited
 patents
bronzeMedal2 out of 3 
 
Chelator LLC
 patents
4. 1 out of 1 
 
Tara Pharmaceutical Industries Ltd
 patent

Years Active: 1993-2018

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17 patents (USPTO):Explore Patents
1. 10112970 - Process for the preparation of 17-desoxy-corticosteroids (2018-10-30),
2. 9334219 - Process for the preparation of a stable polymorphic form of Atovaquone (2016-05-10),
3. 7696356 - Process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one and ondansetron therefrom (2010-04-13),
4. 7288660 - Process for preparing ondansetron hydrochloride dihydrate having a defined particle size (2007-10-30),
5. 7227021 - Process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid (2007-06-05),
6. 7064205 - Process for preparing 1-methoxymethyl-5,5-diphenylbarbituric acid (2006-06-20),
7. 6583182 - Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis (2003-06-24),
8. 6576760 - Processes for synthesis of cyclic and linear polyamine chelators containing N-monosubstituted coordinating arms (2003-06-10),
9. 6469162 - Compounds with chelation affinity and selectivity for first transition series elements: use in medical therapy and diagnosis (2002-10-22),
10. 6387891 - COMPOUNDS WITH CHELATION AFFINITY AND SELECTIVITY FOR FIRST TRANSITION SERIES ELEMENTS AND THEIR USE IN COSMETICS AND PERSONAL CARE PRODUCTS, INHIBITION OF METALLOENZYMES, AND INHIBITION OF REPERFUSION INJURY (2002-05-14),
11. 6264966 - Compounds with chelation affinity and selectivity for first transition elements and their use in cosmetics and personal care products, inhibition of metalloenzymes, and inhibition of reperfusion injury (2001-07-24),
12. 6165996 - Compounds with chelation affinity selectivity for first transition (2000-12-26),
13. 5874573 - Compounds with chelation affinity and selectivity for first transition (1999-02-23),
14. 5593659 - MRI image enchancement of bone and related tissue using complexes of (1997-01-14),
15. 5409689 - MRI image enhancement using complexes of paramagnetic cations and amine (1995-04-25),

Title: Rosa L Cyjon: Innovator in Pharmaceutical Chemistry

Introduction

Rosa L Cyjon is a prominent inventor based in Haifa, Israel, known for her significant contributions to pharmaceutical chemistry. With a remarkable portfolio of 17 patents, she has made strides in the development of corticosteroid derivatives and stable polymorphic forms of pharmaceutical compounds.

Latest Patents

Among her latest innovations is a process for the preparation of 17-desoxy-corticosteroids. This invention provides an improved method for synthesizing 17-desoxy corticosteroid derivatives in a single chemical step. The process involves reacting a 17-hydroxy starting material with an excess of Trimethylsilyl Iodide, which is particularly advantageous for preparing derivatives with halogen groups at specific positions. Another notable patent is for the preparation of a stable polymorphic form of Atovaquone. This process results in a stable polymorph III of Atovaquone, characterized by distinct peaks at various degrees, achieved through a specific heating and cooling process.

Career Highlights

Rosa has worked with notable companies in the pharmaceutical industry, including Concat Ltd. and Taro Pharmaceutical Industries Limited. Her work has significantly impacted the field, showcasing her expertise in developing innovative pharmaceutical processes.

Collaborations

Throughout her career, Rosa has collaborated with esteemed colleagues such as Harry S Winchell and Joseph Y Klein. These partnerships have further enhanced her contributions to the field of pharmaceutical chemistry.

Conclusion

Rosa L Cyjon's innovative work in pharmaceutical chemistry has led to significant advancements in the preparation of corticosteroid derivatives and Atovaquone. Her contributions continue to influence the industry and inspire future innovations.

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